Influence of N (2)-substitution in the alkylation of (4S)-alkyl-2, 4-dihydro-1H-pyrazino [2, 1-b] quinazoline-3, 6-diones

…, FL Buenadicha, M Soellhuber, C Avendano

文献索引：Buenadicha, Felix L.; Avendano, Carmen; Soellhuber, Monica Tetrahedron Asymmetry, 1998 , vol. 9, # 23 p. 4275 - 4284

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被引用次数: 9

摘要

1-Alkylation of O (3)-lactim, N (11)-azaenolate dilithium species derived from N (2)–H compounds 1a and 1b and the lithium azaenolates derived from the N (2)-phenyl and N (2)- (1-arylethyl) substituted compounds 2, 3 and 4 is studied. In 1 the trans-diastereoselectivity