1. Pharmazie. 1992 Apr;47(4):249-51. Synthesis and pharmacology of 3-aryl-5,6-dihydro-6-oxo- 1(4H)-pyridazineacetic acid derivatives. ... The title compounds were prepared by alkylation of 6-aryl-4,5-dihydro-3(2H)-pyridazinones with esters of alpha-bromoacetic acid. ...