Journal of Fluorine Chemistry

Selective mono-fluorination of diols via a cyclic acetal of N, N-diethyl-4-methoxybenzamide

M Suwada, T Fukuhara, S Hara

文献索引：Suwada, Mitsuhiro; Fukuhara, Tsuyoshi; Hara, Shoji Journal of Fluorine Chemistry, 2007 , vol. 128, # 10 p. 1121 - 1125

全文：HTML全文

被引用次数: 3

摘要

Selective mono-fluorination of 1, 2-and 1, 3-diols was achieved using N, N-diethyl-4- methoxybenzamide diethyl acetal and Et3N-3HF. The reaction proceeds through a cyclic acetal of the benzamide, and only one hydroxy group was fluorinated and another one was acylated.