Suzuki cross-coupling reactions of 3-pyrroleboronic acid derivatives with haloaromatics and the reverse process ie, the coupling of 3-iodo (bromo) pyrroles with arylboronic acids have been investigated as a potential key step in the synthesis of ()-rhazinilam and analogues. It was found that 3-iodo-2-formyl-1-tosylpyrroles efficiently coupled with a variety of arylboronic acids in the presence of PdCl2 (dppf) as catalyst. This catalytic system is ...
