Copper (I)??Catalyzed Cascade Synthesis of 2??Substituted 1, 3??Benzothiazoles: Direct Access to Benzothiazolones

S Murru, P Mondal, R Yella…

文献索引：Murru, Siva; Mondal, Pravat; Yella, Ramesh; Patel, Bhisma K. European Journal of Organic Chemistry, 2009 , # 31 p. 5406 - 5413

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被引用次数: 32

摘要

Abstract An efficient cascade process for the preparation of 2-substituted 1, 3- benzothiazoles directly from 2-haloaryl isothiocyanates and O or S nucleophiles by a Cu- catalyzed, intramolecular, C–S bond formation has been developed. This cascade method is viable for the efficient syntheses of both O-and S-substituted 1, 3-benzothiazoles. Furthermore, 1, 3-benzothiazol-2 (3H)-ones having an alkyl group allow easy access to 1, ...