Combinatorial synthesis of substituted thieno [3, 2-b] pyridines and other annulated heterocycles via new SN2→ Thorpe− Ziegler→ Thorpe− Guareschi domino …

AM Shestopalov, LA Rodinovskaya…

文献索引：Shestopalov, Anatoliy M.; Rodinovskaya, Lyudmila A.; Shestopalov, Alexander A. Journal of Combinatorial Chemistry, 2010 , vol. 12, # 1 p. 9 - 12

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被引用次数: 23

摘要

Known methods of synthesis of thieno [3, 2-b] pyridines are significantly underrepresented compared to available information on thieno [2, 3-b] pyridines. 1, 2 Nevertheless, several synthetic pathways toward thieno [3, 2-b] pyridines have been previously described in the literature. 3-6 A thieno [3, 2-b] pyridine structure can be approached via several pathways (Figure 1), all of which require synthesis or in situ generation of 3-aminothiophene. ...