Porphyrin-templated synthetic G-quartet (PorphySQ): a second prototype of G-quartet-based G-quadruplex ligand

…, R Haudecoeur, S Vuong, P Richard, F Denat…

文献索引：Xu, Hai-Jun; Stefan, Loic; Haudecoeur, Romain; Vuong, Sophie; Richard, Philippe; Denat, Franck; Barbe, Jean-Michel; Gros, Claude P.; Monchaud, David Organic and Biomolecular Chemistry, 2012 , vol. 10, # 27 p. 5212 - 5218

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被引用次数: 24

摘要

Template-assembled synthetic G-quartet (TASQ) has been reported recently as a G- quadruplex ligand interacting with DNA according to an unprecedented, nature-inspired 'like likes like'approach, based on the association between two G-quartets, one being native (quadruplex) and the other one artificial (ligand). Herein, a novel TASQ-based ligand is designed, synthesized and its quadruplex-recognition properties are evaluated in vitro: ...