ChemMedChem

Synthesis and Biological Evaluation of 2??Arylamino??5??(3′??Indolyl)??1, 3, 4??Oxadiazoles as Potent Cytotoxic Agents

MP Tantak, A Kumar, B Noel, K Shah…

文献索引：Tantak, Mukund P; Kumar, Anil; Noel, Brett; Shah, Kavita; Kumar, Dalip ChemMedChem, 2013 , vol. 8, # 9 p. 1468 - 1474

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被引用次数: 9

摘要

The indole nucleus is a privileged scaffold that is highly prevalent in natural and synthetic compounds of medicinal interest.[1] It is found in many clinical therapeutic agents (eg, indomethacin, indorenate and indoramin) and endogenous biologically active substances (eg, serotonin, melatonin, tryptophan and brassinin). Molecules containing an indole nucleus display a diverse range of biological activities, such as anticancer, antidiabetic, ...