Thieno [3, 2-b] pyridine. I. The Preparation and Properties of an S-Isosteric 8-Hydroxyquinoline1

JT Sheehan, GJ Leitner

文献索引：Sheehan; Leitner Journal of the American Chemical Society, 1952 , vol. 74, p. 5501

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被引用次数: 4

摘要

Aside from the thianaphthene derivatives relatively little has been reported about other condensed ring systems of thiophene. For the preparation of some S-isosteric analogs3 of Pamaquine as antimalarials the route chosen was via 3-hydroxythieno (3, 2-b) pyridine, an isoster of S-hydroxyq~ inoline.~ The formation of this compound is intimated by Plazek and Suehardas in their synthesis of 6-thiopyrindigo (Fig. 1); however, its isolation was not ...