Tetrahedron

Regioselective monobromination of substituted phenols in the presence of β-cyclodextrin

P Suresh, S Annalakshmi, K Pitchumani

文献索引：Suresh, Palaniswamy; Annalakshmi, Subramanian; Pitchumani, Kasi Tetrahedron, 2007 , vol. 63, # 23 p. 4959 - 4967

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被引用次数: 15

摘要

Cyclodextrin acts as a restricting nanovessel to enhance regioselectivity in bromination of substituted phenols such as 3-nitrophenol, 2-chlorophenol, 3-chlorophenol, and 4- chlorophenol. In contrast to solution bromination, cyclodextrin facilitates regioselective monobromination and formation of polybrominated products are substantially reduced. Selectivities in brominations are also observed in water and in the solid state. The ...