A remarkably simple N-formylation of anilines using polyethylene glycol

…, P Balasubramanyam, B Veeranjaneyulu, DN Kumar

文献索引：Das, Biswanath; Krishnaiah, Maddeboina; Balasubramanyam; Veeranjaneyulu, Boyapati; Nandan Kumar Tetrahedron Letters, 2008 , vol. 49, # 14 p. 2225 - 2227

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被引用次数: 89

摘要

Various methods are available for N-formylation of amines. 6, 7, 8, 9, 10, 11, 12, 13, 14 and 15 However, many of these methods suffer from different drawbacks such as the application of expensive and toxic formylating agents and catalysts, long reaction times, high temperatures and the formation of by-products. ... In continuation of our work 16 and 17 on the application of polyethylene glycol (PEG) to carry out organic synthesis, we have observed that the N-formylation of aniline ...