Synthesis and biological properties of 2-(tetrahydropyran-4-yl) thiazoles

…, SA Vartanyan, RR Safrazbekyan, DZ Partev

文献索引：Kuroyan, R. A.; Markosyan, A. I.; Vartanyan, S. A.; Safrazbekyan, R. R.; Partev, D. Z. Pharmaceutical Chemistry Journal, 1982 , vol. 16, # 8 p. 607 - 611 Khimiko-Farmatsevticheskii Zhurnal, 1982 , vol. 16, # 8 p. 943 - 946

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摘要

The present communication describes the synthesis of substituted 2-(tetrahydropyran-4- yl)thiazoles (IVa-i) from tetrahydropyran-4-carboxylic acids (Ia-d) [4, 5]. The latter were converted into their amides (IIa-d), treatment of which with phosphorus pentasulfide gave the thioamides ...