Citalopram hydrobromide: degradation product characterization and a validated stability-indicating LC-UV method

M Sharma, PR Jawa, RS Gill, G Bansal

文献索引：Sharma, Manav; Jawa, Parikshit R.; Gill, Ravinder S.; Bansal, Gulshan Journal of the Brazilian Chemical Society, 2011 , vol. 22, # 5 p. 836 - 848

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被引用次数: 11

摘要

ABSTRACT Five degradation products (IV) of citalopram hydrobromide (CTL) were formed under different forced degradation conditions. Products I and II were formed under hydrolytic conditions while product III-V were formed under photolytic conditions. Products II and IV were found known impurities as citalopram carboxamide and citalopram N-oxide, respectively. Product I was found to be a new impurity which was characterized as 3- ...