Synthesis and antifungal evaluation of pentyloxyl-diphenylisoxazoloyl pneumocandins and echinocandins

…, K Herath, JN Kahn, P Mann, G Abruzzo…

文献索引：Singh, Sheo B.; Herath, Kithsiri; Kahn, Jennifer Nielsen; Mann, Paul; Abruzzo, George; Motyl, Mary Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 11 p. 3253 - 3256

全文：HTML全文

被引用次数: 4

摘要

Echinocandins and pneumocandins are classes of lipocyclohexapeptides that are broad spectrum antifungal agents. They inhibit fungal specific 1, 3-β-glucan synthase activity which is an essential component of the fungal cell wall. Chemical modifications of these two ...