Solvent??Free Approach to 3, 4??Dihydropyrimidin??2 (1 H)??(thio) ones: Biginelli Reaction Catalyzed by a Wells–Dawson Reusable Heteropolyacid

…, AG Sathicq, JC Autino, G Baronetti…

文献索引：Romanelli, Gustavo P.; Sathicq, Angel G.; Autino, Juan C.; Baronetti, Graciela; Thomas, Horacio J. Synthetic Communications, 2007 , vol. 37, # 22 p. 3907 - 3916

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被引用次数: 24

摘要

Abstract The Biginelli reaction is performed in an efficient, simple, solvent??free procedure, using a small amount of H6P2W18O62· 24H2O, a reusable heteropolyacid catalyst with Wells–Dawson structure. Both aromatic and aliphatic aldehydes, and different β??dicarbonyl compounds and urea or thiourea, were used as starting materials. Seventeen examples of dihydropyrimidinones and dihydropyrimidinethiones were prepared by heating the ...