Laccase-catalyzed domino reaction between catechols and 6-substituted 1, 2, 3, 4-tetrahydro-4-oxo-2-thioxo-5-pyrimidinecarbonitriles for the synthesis of …

HT Abdel-Mohsen, J Conrad…

文献索引：Abdel-Mohsen, Heba T.; Conrad, Juergen; Beifuss, Uwe Journal of Organic Chemistry, 2013 , vol. 78, # 16 p. 7986 - 8003

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被引用次数: 12

摘要

The laccase-catalyzed domino reaction between catechols and 6-substituted 1, 2, 3, 4- tetrahydro-4-oxo-2-thioxo-5-pyrimidinecarbonitriles using aerial O2 as the oxidant delivers new pyrimidobenzothiazole derivatives. The complete structure elucidation of the ring- proton deficient heterocyclic products and the unambiguous determination of the regioselectivity of the reactions have been achieved by extended NMR spectroscopic ...