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举例 :可输入Filippa Pettersson 或者 Cancer Res. 75(6) , 1102-12, (2015) 或者10.1002/anie.201600521

2-cyano-1, 3-dicarbonyl compounds with antiallergic activity

DR Buckle, BCC Cantello, H Smith…

文献索引：Buckle,D.R. et al. Journal of Medicinal Chemistry, 1977 , vol. 20, p. 265 - 269

全文：HTML全文

被引用次数: 21

摘要

A number of 2-cyanoindan-1, 3-diones and 3-cyano-4-hydroxycoumarins have been prepared and assessed for potential antiallergy activity as measured by their ability to inhibit passive cutaneous anaphylaxis in the rat, mediated by rat serum containing antigen specific IgE. The structural requirements for activity were similar not only for both series of compounds but also for the analogous 2-nitroindan-l, 3-diones and 4-hydroxy-3- ...

2-bromo-6,7-dimethyl naphtho-1,4-quinone结构式

2-bromo-6,7-dim...

~%

2-azido-6,7-dimethylnaphthalene-1,4-dione结构式

2-azido-6,7-dim...

1,4-Naphthalenedione,6,7-dimethyl-结构式

1,4-Naphthalene...

~%

2-azido-6,7-dimethylnaphthalene-1,4-dione结构式

2-azido-6,7-dim...

1,2-diethyl benzene结构式

1,2-diethyl benzene

~%

5,6-diethyl-1,3-dioxoindene-2-carbonitrile结构式

5,6-diethyl-1,3...

3-(3,4-Diethyl-benzoyl)-propansaeure结构式

3-(3,4-Diethyl-...

~%

5,6-diethyl-1,3-dioxoindene-2-carbonitrile结构式

5,6-diethyl-1,3...

6,7-diethyl-3,4-dihydro-2H-naphthalen-1-one结构式

6,7-diethyl-3,4...

~%

5,6-diethyl-1,3-dioxoindene-2-carbonitrile结构式

5,6-diethyl-1,3...

2-chloro-6,7-diethylnaphthalene-1,4-dione结构式

2-chloro-6,7-di...

~%

5,6-diethyl-1,3-dioxoindene-2-carbonitrile结构式

5,6-diethyl-1,3...

6,7-diethyl-4-hydroxynaphthalene-1,2-dione结构式

6,7-diethyl-4-h...

~%

5,6-diethyl-1,3-dioxoindene-2-carbonitrile结构式

5,6-diethyl-1,3...

4-(3,4-diethylphenyl)butanoic acid结构式

4-(3,4-diethylp...

~%

5,6-diethyl-1,3-dioxoindene-2-carbonitrile结构式

5,6-diethyl-1,3...

2-azido-6,7-diethylnaphthalene-1,4-dione结构式

2-azido-6,7-die...

~%

5,6-diethyl-1,3-dioxoindene-2-carbonitrile结构式

5,6-diethyl-1,3...

2-bromo-6,7-dimethyl naphtho-1,4-quinone结构式

2-bromo-6,7-dim...

~%

5,6-dimethyl-1,3-dioxoindene-2-carbonitrile结构式

5,6-dimethyl-1,...

1,4-Naphthalenedione,6,7-dimethyl-结构式

1,4-Naphthalene...

~%

5,6-dimethyl-1,3-dioxoindene-2-carbonitrile结构式

5,6-dimethyl-1,...

2-azido-6,7-dimethylnaphthalene-1,4-dione结构式

2-azido-6,7-dim...

~%

5,6-dimethyl-1,3-dioxoindene-2-carbonitrile结构式

5,6-dimethyl-1,...

2-bromo-5-methylnaphthalene-1,4-dione结构式

2-bromo-5-methy...

~%

4-methyl-1,3-dioxoindene-2-carbonitrile结构式

4-methyl-1,3-di...

2,3-萘二甲酸二甲酯结构式

2,3-萘二甲酸二甲酯

乙腈结构式

~%

1,3-dioxocyclopenta[b]naphthalene-2-carbonitrile结构式

1,3-dioxocyclop...

苯酐结构式

氰基乙酸结构式

~%

1H-Indene-2-carbonitrile,2,3-dihydro-1,3-dioxo-结构式

1H-Indene-2-car...

1,2-BENZENEDICARBOXYLIC ACID,4-CHLORO-,1,2-DIMETHYL ESTER结构式

1,2-BENZENEDICA...

乙腈结构式

~%

5-chloro-1,3-dioxoindene-2-carbonitrile结构式

5-chloro-1,3-di...

3-(3,4-Diethyl-benzoyl)-propansaeure结构式

3-(3,4-Diethyl-...

~%

4-(3,4-diethylphenyl)butanoic acid结构式

4-(3,4-diethylp...

1,2-diethyl benzene结构式

1,2-diethyl benzene

~%

4-(3,4-diethylphenyl)butanoic acid结构式

4-(3,4-diethylp...

4-甲基苯酐结构式

氰基乙酸结构式

~%

5-methyl-1,3-dioxoindene-2-carbonitrile结构式

5-methyl-1,3-di...

1,2-diethyl benzene结构式

1,2-diethyl benzene

~%

6,7-diethyl-3,4-dihydro-2H-naphthalen-1-one结构式

6,7-diethyl-3,4...

3-(3,4-Diethyl-benzoyl)-propansaeure结构式

3-(3,4-Diethyl-...

~%

6,7-diethyl-3,4-dihydro-2H-naphthalen-1-one结构式

6,7-diethyl-3,4...

1,2-diethyl benzene结构式

1,2-diethyl benzene

~%

6,7-diethyl-4-hydroxynaphthalene-1,2-dione结构式

6,7-diethyl-4-h...

3-(3,4-Diethyl-benzoyl)-propansaeure结构式

3-(3,4-Diethyl-...

~%

6,7-diethyl-4-hydroxynaphthalene-1,2-dione结构式

6,7-diethyl-4-h...

6,7-diethyl-4-hydroxynaphthalene-1,2-dione结构式

6,7-diethyl-4-h...

~%

2-chloro-6,7-diethylnaphthalene-1,4-dione结构式

2-chloro-6,7-di...

1,2-diethyl benzene结构式

1,2-diethyl benzene

~%

2-chloro-6,7-diethylnaphthalene-1,4-dione结构式

2-chloro-6,7-di...

3-(3,4-Diethyl-benzoyl)-propansaeure结构式

3-(3,4-Diethyl-...

~%

2-chloro-6,7-diethylnaphthalene-1,4-dione结构式

2-chloro-6,7-di...

6,7-diethyl-3,4-dihydro-2H-naphthalen-1-one结构式

6,7-diethyl-3,4...

~%

2-chloro-6,7-diethylnaphthalene-1,4-dione结构式

2-chloro-6,7-di...

4-(3,4-diethylphenyl)butanoic acid结构式

4-(3,4-diethylp...

~%

2-chloro-6,7-diethylnaphthalene-1,4-dione结构式

2-chloro-6,7-di...

2-chloro-6,7-diethylnaphthalene-1,4-dione结构式

2-chloro-6,7-di...

~%

2-azido-6,7-diethylnaphthalene-1,4-dione结构式

2-azido-6,7-die...

1,2-diethyl benzene结构式

1,2-diethyl benzene

~%

2-azido-6,7-diethylnaphthalene-1,4-dione结构式

2-azido-6,7-die...

3-(3,4-Diethyl-benzoyl)-propansaeure结构式

3-(3,4-Diethyl-...

~%

2-azido-6,7-diethylnaphthalene-1,4-dione结构式

2-azido-6,7-die...

6,7-diethyl-3,4-dihydro-2H-naphthalen-1-one结构式

6,7-diethyl-3,4...

~%

2-azido-6,7-diethylnaphthalene-1,4-dione结构式

2-azido-6,7-die...

6,7-diethyl-4-hydroxynaphthalene-1,2-dione结构式

6,7-diethyl-4-h...

~%

2-azido-6,7-diethylnaphthalene-1,4-dione结构式

2-azido-6,7-die...

4-(3,4-diethylphenyl)butanoic acid结构式

4-(3,4-diethylp...

~%

2-azido-6,7-diethylnaphthalene-1,4-dione结构式

2-azido-6,7-die...