Tetrahedron

Cross-coupling reaction on N-(3, 5-dibromo-2-pyridyl) piperazines: regioselective synthesis of 3, 5-disubstituted pyridylpiperazines

H Hikawa, Y Yokoyama

文献索引：Hikawa, Hidemasa; Yokoyama, Yuusaku Tetrahedron, 2010 , vol. 66, # 49 p. 9552 - 9559

全文：HTML全文

被引用次数: 3

摘要

Unsymmetrical 3, 5-disubstituted pyridylpiperazines were prepared from tribromopyridine in three coupling reactions. Key to the success of the syntheses is the palladium-catalyzed regioselective cross-coupling reaction in the 3-position of N-(3, 5-dibromo-2-pyridyl) piperazines.