A robust platform for the synthesis of new tetracycline antibiotics

C Sun, Q Wang, JD Brubaker, PM Wright…

文献索引：Broom, Nigel J. P.; Sammes, Peter G. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 465 - 470

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被引用次数: 71

摘要

... elimination of phenylsulfenic acid.(22) The use of phthalide and cyanophthalide anions as nucleophilic components was described by Broom and Sammes (eq 2 ... the AB precursor 1 in optically active form; the more recent of these was scaled to prepare >40 g of crystalline ...