Discovery of atrop fixed alkoxy-aminobenzhydrol derivatives: Novel, highly potent and orally efficacious squalene synthase inhibitors

M Ichikawa, A Yokomizo, M Itoh, N Haginoya…

文献索引：Bioorganic and Medicinal Chemistry, , vol. 19, # 17 p. 5207 - 5224

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被引用次数: 6

摘要

... Bioorganic & Medicinal Chemistry. ... 8 CSI activity was used as a potential parameter to predict in vivo CSI activity, and was considered more important than SSI activity as a guide to afford effective cholesterol-lowering medicine. ...