Catalytic Asymmetric Reaction with Water: Enantioselective Synthesis of α??Hydroxyesters by a Copper–Carbenoid O H Insertion Reaction

SF Zhu, C Chen, Y Cai, QL Zhou

文献索引：Zhu, Shou-Fei; Chen, Chao; Cai, Yan; Zhou, Qi-Lin Angewandte Chemie - International Edition, 2008 , vol. 47, # 5 p. 932 - 934

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被引用次数: 103

摘要

As one of the most abundant, safe, environmentally benign, and cost-efficient resources, water has been widely used in chemical synthesis and production.[1] However, catalytic asymmetric transformations using water as a reactant remain a great challenge to chemists, and successful examples are very limited.[2] Transition-metal-catalyzed asymmetric insertion of α-diazoesters into the OÀH bond of water provides an extremely simple ...