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AlCl 3 induced (hetero) arylation of 2, 3-dichloroquinoxaline: a one-pot synthesis of mono/disubstituted quinoxalines as potential antitubercular agents

…, R Kapavarapu, GR Krishna, MVB Rao, K Chatti…

文献索引:Kumar, K. Shiva; Rambabu; Sandra, Sandhya; Kapavarapu, Ravikumar; Krishna, G. Rama; Basaveswara Rao; Chatti, Kiranam; Reddy, C. Malla; Misra, Parimal; Pal, Manojit Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 5 p. 1711 - 1722

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被引用次数: 26

摘要

A direct and single-step method has been developed for the synthesis of mono and 2, 3- disubstituted quinoxalines by using a AlCl3 induced (hetero) arylation of 2, 3- dichloroquinoxaline. Both symmetrical and unsymmetrical 2, 3-disubstituted quinoxalines can be prepared conveniently by using this method under appropriate reaction conditions. The reaction proceeds via C–C bond formation and can be utilized for the preparation of a ...