New prenylamine-analogues: investigations of their influence on calcium-dependent biological systems

…, P Zandberg, R Mannhold, H Timmerman

文献索引：Caldirola, P.; Zandberg, P.; Mannhold, R.; Timmerman, H. European Journal of Medicinal Chemistry, 1993 , vol. 28, # 7-8 p. 555 - 568

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被引用次数: 2

摘要

Abstract Chemically, prenylamine belongs to the diphenylalkylamine class. Compounds of this class are calcium antagonists with a broad spectrum of activities due to their influence on both extracellular and intracellular sites. In the present study the calcium antagonistic profile of a recently developed new series of prenylamine analogues has been investigated using different in vitro systems. The inhibiting concentrations for the most active compound ...