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Synthesis

Oxidation of methyl heteroaryls with molecular oxygen: A facile synthesis of 2-[n-(tert-butoxycarbonyl) amino]-4-pyridinecarbaldehyde

…, R Aslanian, M de Lera Ruiz, KD McCormick

文献索引:Berlin, Michael; Aslanian, Robert; Ruiz, Manuel De Lera; McCormick, Kevin D. Synthesis, 2007 , # 16 p. 2529 - 2533

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被引用次数: 1

摘要

Abstract Oxidation of nitrogen-based methyl heteroaryls with molecular oxygen resulted in the formation of the corresponding benzyl alcohols. While experimentally easy and amenable to large-scale preparations, this approach has limitations with respect to the particular nature of heterocyclic substrates. Using this methodology, the title compound, 2-[N- (tert-butoxycarbonyl) amino]-4-pyridinecarbaldehyde, considered to be a versatile ...