Expedient synthesis of deuterium??labelled amides within micro??reactors

J Hooper, P Watts

文献索引：Hooper, Julian; Watts, Paul Journal of Labelled Compounds and Radiopharmaceuticals, 2007 , vol. 50, # 3 p. 189 - 196

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被引用次数: 16

摘要

Abstract The pharmaceutical industry relies heavily on the synthesis of small quantities (10– 500 mg) of stable, isotopically labelled compounds in the evaluation of new drug candidates for metabolism studies. As a result of the phenomenal cost of labelled materials even the preparation of small quantities can be extremely expensive.