Photooxidation and phototoxicity of π-extended squaraines

V Rapozzi, L Beverina, P Salice…

文献索引：Rapozzi, Valentina; Beverina, Luca; Salice, Patrizio; Pagani, Giorgio A.; Camerin, Monica; Xodo, Luigi E. Journal of Medicinal Chemistry, 2010 , vol. 53, # 5 p. 2188 - 2196

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被引用次数: 25

摘要

This paper describes the synthesis of π-extended squaraines and their photooxidation properties and gives an in-depth characterization of these molecules as photosensitizing agents. Squaraines show a strong absorption in the tissue transparency window (600− 800 nm), and upon irradiation, they undergo a photooxidation process, leading to the formation of peroxide and hydroperoxide radicals according to a type I radical chain process. ...