Four protected oligopeptolides of L-leucine and L-2-hydroxy-4-methylpentanoic acid, with benzyloxycarbonyl as N-protecting and t-butyl as C-protecting group, have been synthesised; the depside linkage was formed by the action of dicyclohexylcarbodi-imide in ethereal pyridine. The action of triethylamine on the chloride hydrochlorides of the deprotected oligopeptolides gave the macromolecular sequential polypeptolides (I; x= 1, 2 ...
[Conroy, Trent; Guo, Jin T.; Linington, Roger G.; Hunt, Nicholas H.; Payne, Richard J. Chemistry - A European Journal, 2011 , vol. 17, # 48 p. 13544 - 13552]
