The action of hypochlorous acid on phosphatidylcholine liposomes in dependence on the content of double bonds. Stoichiometry and NMR analysis

…, OM Panasenko, J Schiller, YA Vladimirov…

文献索引：Arnhold, J.; Panasenko, O. M.; Schiller, J.; Vladimirov, Yu. A.; Arnold, K. Chemistry and Physics of Lipids, 1995 , vol. 78, # 1 p. 55 - 64

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被引用次数: 80

摘要

Kinetics of the consumption of hypochlorous acid in its reaction with double bonds of unsaturated phospholipids and fatty acids were measured using luminol chemiluminescence. Stoichiometry ratios between the consumption of HOC1/OC1− and the loss of double bonds vary from 2: 1 to 1: 1. Hightst values were found in DMPC liposomes containing 5 mol% oleic acid or OPPC. With increasing content of double bonds or higher ...