Medicinal Chemistry Research

In-silico design, synthesis and evaluation of novel DNA-gyrase B inhibitors

U Shiroya, M Patel

文献索引：Shiroya, Umesh; Patel, Milan Medicinal Chemistry Research, 2013 , vol. 22, # 11 p. 5227 - 5235

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被引用次数: 1

摘要

Abstract 2-Quinolones are an important class of compounds, isomeric to 4-quinolones. They may become promising candidates for exploiting more useful therapeutically active molecules. DNA-gyrase has drawn much attention as a selected target for finding potent anti- bacterial agents against multi-drug resistant strains such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, and penicillin-resistant ...