Discovery of novel tricyclic compounds as squalene synthase inhibitors

M Ichikawa, M Ohtsuka, H Ohki, N Haginoya…

文献索引：Bioorganic and Medicinal Chemistry, , vol. 20, # 9 p. 3072 - 3093

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被引用次数: 10

摘要

... Bioorganic & Medicinal Chemistry. ... 3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, statins, were regarded as the first line medicine for the ... Medicinal chemistry efforts to identify small and efficient squalene synthase inhibitors have been reported by some research ...