Synthesis and characterization of hydroxylated mesocarb metabolites for doping control

…, A Leinonen, J Yli??Kauhaluoma

文献索引：Vahermo, Mikko; Suominen, Tina; Leinonen, Antti; Yli-Kauhaluoma, Jari Archiv der Pharmazie, 2009 , vol. 342, # 4 p. 201 - 209

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被引用次数: 12

摘要

Abstract The synthesis and method of analysis of hydroxylated mesocarb metabolites are described. Six potential hydroxylated mesocarb metabolites were prepared, characterized, and compared with the mesocarb metabolites synthesized enzymatically in vitro using human liver proteins and also compared with metabolites extracted from human urine after oral administration of mesocarb. p-Hydroxymesocarb was the most prevalent metabolite ( ...