Chemical Communications

Efficient base catalyzed alkylation reactions with aziridine electrophiles

TA Moss, A Alba, D Hepworth, DJ Dixon

文献索引：Moss, Thomas A.; Alba, Aurelie; Hepworth, David; Dixon, Darren J. Chemical Communications, 2008 , # 21 p. 2474 - 2476

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被引用次数: 8

摘要

N-Mesitylene sulfonyl and N-tosyl aziridines have been identified as effective electrophiles in alkylation reactions of carbon acids catalyzed by the organic phosphorine base BEMP; yields of up to 99% for a range of pro-nucleophiles under mild reaction conditions are reported.