Journal of medicinal chemistry

Synthesis and cyclic GMP phosphodiesterase inhibitory activity of a series of 6-phenylpyrazolo [3, 4-d] pyrimidones

B Dumaître, N Dodic

文献索引：Journal of Medicinal Chemistry, , vol. 39, # 8 p. 1635 - 1644

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被引用次数: 60

摘要

... Journal of Medicinal Chemistry. ... Chemistry. The pyrimidinone basic structure was synthesized according to Scheme 1. The appropriate heterocyclic o-aminonitrile was reacted with a substituted benzoyl chloride to give ...