Synthesis and In Vitro Evaluation of 2??Aminoquinazolin??4 (3H)??one??Based Inhibitors for tRNA??Guanine Transglycosylase (TGT)

EA Meyer, M Furler, F Diederich, R Brenk…

文献索引：Helvetica Chimica Acta, , vol. 87, # 6 p. 1333 - 1356

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被引用次数: 25

摘要

... e) H2 , Pd/C (10%), EtOH, 708, 4 h; 46%. f) HCl, EtOH, 708, 4 h; 93%. tol toluyl. Helvetica Chimica Acta ± Vol. 87 (2004) 1337 Fig. 3. Biological activity (Ki values) of the first series of TGT inhibitors Page 6. resulted in a substantial loss of activity. ...