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Syntheses and antifungal activity of pseudomycin side-chain analogues. Part 1

J Jamison, S Levy, X Sun, D Zeckner, W Current…

文献索引:Jamison, James; Levy, Stuart; Sun, Xicheng; Zeckner, Doug; Current, William; Zweifel, Mark; Rodriguez, Michael; Turner, William; Chen, Shu-Hui Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 18 p. 2101 - 2105

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被引用次数: 13

摘要

We have described herein the syntheses of three novel series of aromatic ring containing pseudomycin side-chain analogues. Preliminary biological evaluations of these analogues clearly indicate that it is possible to synthesize rigid pseudomycin side-chain analogues without compromising in vitro antifungal activity.