Aqueous hydrolysis of pyrazol-1-ylacetates

KS Badalyan, AG Asratyan, OS Attaryan

文献索引：Badalyan; Asratyan; Attaryan Russian Journal of General Chemistry, 2012 , vol. 82, # 5 p. 946 - 946

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被引用次数: 2

摘要

The pyrazole esters (n= 2) are known to be hydrolyzed in the presence of bases [1–3]. We found that pyrazole esters I–III (n= 1) are hydrolyzed with water in the absence of bases. 15 h. Yield 2.8 g (68%). The isomers molar ratio is 3: 5–3: 1, respectively. White crystals, mp 160–163 C (water). IR spectrum, ν, cm–1: 1530 (ring), 1680 (C= O), 3100–3400 (COOH). 1Н NMR spectrum (DMSO-d6), δ, ppm (J, Hz): 2.19 s (3H, 3-CH3), 2.22 s (3H, 5-CH3), 4.70 s ...