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The Total Synthesis of Sparteine and an Isosparteine by Reductive Cyclization1

NJ Leonard, RE Beyler

文献索引:Leonhard; Beyler Journal of the American Chemical Society, 1950 , vol. 72, p. 1316,1322

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被引用次数: 52

摘要

Summary Syntheses of two model high-energy phosphorus compounds derived from glycine are described. B 0th ph thal ylglycyl di benzyl phosphate and N-carbobenzoxyglycyl dibenzyl phosphate have the properties of acylating agents. In addition, it has been demonstrated that phthalylglycyl dibenzyl phosphate reacts with glycine and with m- phenylalanine to form phthalyl peptides under simulated physiological conditions. These ...