Tetrahedron

A facile method for the rapid and selective deprotection of methoxymethyl (MOM) ethers

JH Han, YE Kwon, JH Sohn

文献索引：Han, Jae Hyun; Kwon, Young Eun; Sohn, Jeong-Hun; Ryu, Do Hyun Tetrahedron, 2010 , vol. 66, # 9 p. 1673 - 1677

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被引用次数: 38

摘要

We describe a rapid and efficient method for selective deprotection of methoxymethyl (MOM) ethers using ZnBr2 and n-PrSH, which completely removed MOM from diverse MOM ethers of primary, secondary, and tertiary alcohols or phenol derivatives. The deprotection takes less than ten minutes with both high yield and selectivity in the presence of other protecting groups. In addition, the rapid deprotection of MOM ethers of tertiary hydroxyls in high yield ...