A new method for stereocontrolled synthesis of substituted tetrahydrothiophenes

AM Ponce, LE Overman

文献索引：Ponce, Andres Molina; Overman, Larry E. Journal of the American Chemical Society, 2000 , vol. 122, # 36 p. 8672 - 8676

全文：HTML全文

被引用次数: 29

摘要

A variety of substituted 3-acyltetrahydrothiophenes can be prepared with high stereoselectivity in 50-70% yield by acid-promoted condensation of mercapto allylic alcohols 1 (X= S) with aldehydes and ketones. The mercapto allylic alcohol must be substituted at ...