Preparations and transformations of bifunctional exo-2-phosphorus substituted bicyclo [2.2. 1] heptanes

AC Peterson, SM Levsen, SE Cremer

文献索引：Peterson, Andrew C.; Levsen, Steven M.; Cremer, Sheldon E. Phosphorus, Sulfur and Silicon and Related Elements, 1996 , vol. 115, p. 241 - 254

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被引用次数: 6

摘要

Abstract The secondary phosphonate ester exo-2-(dimethoxyphosphoryl) bicyclo [2.2. 1] heptane 1 was prepared by literature methods on a mole scale. This synthetic method was extended to include the stereoselective preparation of the exo-diethyl phosphonate analog 3 in 71% yield. Derivatization of these exo-phos-phonates 1 and 3 required vigorous conditions, but proceeded in moderate to high yields. The configuration about carbon-2 ...