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The preparation of 4, 5-dihydro-3-aryl-naphth-[1, 2-c]-isoxazoles from dilithiated 1-tetralone oxime and aromatic esters

…, CD Hornsby, SL Studer-Martinez

文献索引:Beam, Charles F.; Schady, Deborah A.; Rose, Kelly L.; Kelley Jr., Wayne; Rakkhit, Ronjay; Hornsby, Christopher D.; Studer-Martinez, Shannon L. Synthetic Communications, 2000 , vol. 30, # 18 p. 3391 - 3404

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被引用次数: 8

摘要

ABSTRACE Dilithiated I-tetralone oxime was prepared in excess lithium diisopropylamide and condensed with a variety of esters followed by acid cyclization of C-acylated intermediates to substituted 4,5-dihydronaphth-[ 1.2-c]- isoxazoles. ... While the syntheses and uses of isoxazoles have received considerable ... [ 1,2-c]isoxazoles4 are very limited. The utilization of one of the well documented ... In an earlier investigationh, we prepared two 4,5-dihydronaphth-[ 1 ...