. beta.-Adrenergic antagonists with multiple pharmacophores: persistent blockade of receptors

…, J Milecki, T Czajkowska, JW Kusiak

文献索引：Pitha; Milecki; Czajkowska; Kusiak Journal of Medicinal Chemistry, 1983 , vol. 26, # 1 p. 7 - 11

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被引用次数: 25

摘要

Results Chemistry. The general structure of@-adrenergic antagonists of the aromatic ether type is aryl-OCH2CHOHCH2NH-alkyl. While compounds with various aromatic residues were found active, the alkyl group has to be secondary or tertiary to obtain a fully active compound. 14