Synthetic route to tricyclic carbon compounds by Friedel–crafts acylation

A Tubul, M Santelli

文献索引：Tubul, Arlette; Santelli, Maurice Journal of the Chemical Society, Chemical Communications, 1988 , # 3 p. 191 - 192

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被引用次数: 4

摘要

Acylation of cyclohexene by cyclohexenyl- or cyclopentenyl-acetyl chloride gave des-A-11 -ox0 or des-~-7-oxo steroids. ... The total synthesis of steroids remains an active area of research although the aim of the studies and the methods used have changed over the years.' Here we propose a one step des-A-11-oxo-steroid (or des-~-7-oxo steroid) synthesis from cyclohexene and cyclopentenylacetyl (or cyclohexenylacetyl) chloride. We have previously shown that ...