Stereochemistry of 1, 4-addition of nucleophiles to ethyl cyclohexylidenecyanoacetates

D Nasipuri, A Sarkar, SK Konar

文献索引：Nasipuri, Dhanonjoy; Sarkar, Ashis; Konar, Samir K. Journal of Organic Chemistry, 1982 , vol. 47, # 15 p. 2840 - 2845

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被引用次数: 11

摘要

The stereochemistry of 1, Caddition of several nucleophiles such as cyanide, sodium borohydride, and methylmagnesium iodide to three substituted ethyl cyclohexylidenecyanoacetates (1-3) has been determined. A higher preference for equatorial attack is observed in these compounds than in related cyclohexanones, which is considerably diminished by the use of aprotic polar eolvents. The results do not show any ...