The Journal of Organic Chemistry

The Synthesis of New Heterocyclic Compounds from 3, 4-Dichlorocoumarins

MS Newman, CY Perry

文献索引：Newman,M.S.; Perry,C.W. Journal of Organic Chemistry, 1963 , vol. 28, p. 116 - 120

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被引用次数: 10

摘要

On treatment with nucleophilic reagents, each of the chlorine atoms in 3, 4- dichlorocoumarins is replaced, that in the 4-position considerably more easily than that in the 3-positi0n.~ Because of this behavior, the synthesis of compounds containing an additional heterocyclic ring fused to the 3, 4-positions of the coumarin nucleus seemed possible. This objective was of interest because compounds having physiological activity ...