Rational design of fluorescein-based fluorescence probes. Mechanism-based design of a maximum fluorescence probe for singlet oxygen

…, Y Urano, K Kikuchi, T Higuchi, T Nagano

文献索引：Umezawa, Naoki; Tanaka, Kumi; Urano, Yasuteru; Kikuchi, Kazuya; Higuchi, Tsunehiko; Nagano, Tetsuo Angewandte Chemie - International Edition, 1999 , vol. 38, # 19 p. 2899 - 2901

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被引用次数: 298

摘要

Fluorescein is one of the best available fluorophores for biological applications, but the factors that control its fluorescence properties are not fully established. Thus, we initiated a study aimed at providing a strategy for rational design of functional fluorescence probes bearing fluorescein structure. We have synthesized various kinds of fluorescein derivatives and examined the relationship between their fluorescence properties and the highest ...