Synthesis, preliminary biological evaluation and molecular modeling of some new heterocyclic inhibitors of TACE

P Sengupta, CS Puri, HA Chokshi, CK Sheth…

文献索引：European Journal of Medicinal Chemistry, , vol. 46, # 11 p. 5549 - 5555

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被引用次数: 7

摘要

... European Journal of Medicinal Chemistry. ... R f : 0.3 (CH 2 Cl 2 -methanol, 9:1); 1 H NMR (δ, DMSO-d 6 ): 10.51 (s, 1H), 8.90 (s, 1H), 8.76 (s, 1H), 8.48 (d, 1H, J = 7.0 Hz), 8.15 (d, 1H, J = 7.5 Hz), 7.61–7.57 (m, 1H), 7.51–7.47 (m, 1H), 7.39 (d, 1H, J = 8.0 Hz), 7.20–7.16 (m, 2H ...