All recorded yields of phenoxyacetone in its synthesis from phenol and chloroacetone are very poor. When sodium phenoxide and chloroacetone reacted in toluene as solvent the yield'was IS%, whereas a 23% yield was founds when phenol, chloroacetone and potassium carbonate interacted using acetone as solvent. Even with bromoacetone the yields from phenol '(53%) or p-creso16 (2747%) leave much to be desired. The story with ...
