Synthesis of a Series of Diphenyl (Arylamino)(Pyridin-3-yl) Methylphosphonates as Potential Antimicrobial Agents
MF Abdel-Megeed, GA El-Hiti, BE Badr…
文献索引：Abdel-Megeed, Mohamed F.; El-Hiti, Gamal A.; Badr, Badr E.; Azaam, Mohamed M. Phosphorus, Sulfur and Silicon and the Related Elements, 2013 , vol. 188, # 7 p. 879 - 885
Diphenyl 1-(arylamino)(pyridin-3-yl)methylphosphonates were obtained in high yields from the reactions of nicotinaldehyde with aromatic amines and triphenylphosphite in the presence of titanium tetrachloride (TiCl 4 ) as a catalyst. The structures of the synthesized compounds were confirmed by IR, 1 H NMR and mass spectral data and their purities were confirmed by elemental analyses. The synthesized α-aminophosphonates showed moderate to high antimicrobial ...
