The Journal of Organic Chemistry

Reductions with NADH models. 3. The high reactivity of Hantzsch amides

G Gelbard, J Lin, N Roques

文献索引：Gelbard, Georges; Lin, Jian; Roques, Nathalie Journal of Organic Chemistry, 1992 , vol. 57, # 6 p. 1789 - 1793

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被引用次数: 20

摘要

Aromatic ketones and aldehydes are rapidly reduced to alcohols by various 1, 4- dihydropyridines, several of which can be considered to be a model of the coenzyme NADH. The reducing agents bear amide groups and are closely related to Hantzsch esters. They exhibit the highest reactivity among NADH models so far described. In mme casea, the rate and completeness of reduction by Hantzsch amides compare favorably with those of ...